Impeding the single-strand annealing pathway of DNA double-strand break repair by withaferin A-mediated FANCA degradation
نویسندگان
چکیده
منابع مشابه
Genetic requirements for the single-strand annealing pathway of double-strand break repair in Saccharomyces cerevisiae.
HO endonuclease-induced double-strand breaks (DSBs) within a direct duplication of Escherichia coli lacZ genes are repaired either by gene conversion or by single-strand annealing (SSA), with > 80% being SSA. Previously it was demonstrated that the RAD52 gene is required for DSB-induced SSA. In the present study, the effects of other genes belonging to the RAD52 epistasis group were analyzed. W...
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ژورنال
عنوان ژورنال: DNA Repair
سال: 2019
ISSN: 1568-7864
DOI: 10.1016/j.dnarep.2019.02.010